Indicated for Sadness, Anger, Worry, Indecision, Sleeplessness. Ignatia amara is a homeopathic remedy commonly used for sadness, worry and sleeplessness. Other indications for its use - the patient is sad, sighing, and moody. It is also a remedy of paradoxicalities - i.e., head better lying on painful side, hunger not improved by eating, thirst during chill, face red during chill, etc. Ignatia is a homeopathic remedy derived from the bean of a small tree that is native to the Philippine Islands and China. Active ingredient: Ignatia amara [HPUS]. Inactive ingredients: Sucrose/lactose pellets.