Indicated for Sadness, Anger, Despair, Indecision, Sleeplessness. Ignatia amara is a homeopathic remedy commonly used for grief, sadness, despair and sleeplessness. Other indications for its use - the patient is sad, sighing, and moody. It is also a remedy of paradoxicalities - i.e., head better lying on painful side, hunger not improved by eating, thirst during chill, face red during chill, etc. Ignatia is a homeopathic remedy derived from the bean of a small tree that is native to the Philippine Islands and China. Active ingredient: Ignatia amara [HPUS]. Inactive ingredient: Alcohol.