Indicated for Gripping pain, Frightful dreams, Sadness, Sleeplessness. Cactus grandiflorus is a homeopathic remedy commonly used for headaches and sadness. The patient is often worse at about noon, lying on left side; walking, going upstairs, 11 am and 11 pm and better in open air. This homeopathic remedy is made from a cactus known as night-blooming Cereus, or Queen of the Night. Active ingredient: Cactus grandiflorus [HPUS]. Inactive ingredients: Sucrose/lactose pellets.